Rauwolfia serpentina is an evergreen shrub (Endress and Bruyns, 2000). More than 100 species are involved in the Rauwolfia genus, and they are inhabitant to tropical and subtropical regions of the world, including Europe, Africa, Asia, Australia, and the Central and South Americas (Vakil ,1955) The family includes 50 species, distributed worldwide in the region of the Himalayas, Indian peninsula, Burma, Indonesia and Sri Lanka and is indigenous to India, Bangladesh and other regions of Asia.9,1 Rauwolfia serpentina is found indigenous to the moist, deciduous forests of South East Asia including Bhutan, China, India, Myanmar, Nepal, Pakistan, Thailand, Viatnam, Sri Lanka, Malaysia, Andaman Islands and Indonesia. Most of the drug is obtained from wild sources in these countries. Dey and De, (2010) and Kavita, (2005).